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Sildigra 100 mg contains sildenafil citrate as its active ingredient, which is primarily used to treat erectile dysfunction (ED) in men by increasing blood flow to the penis during sexual stimulation. However, sildenafil citrate, the same active ingredient in Sildigra, is also used to treat pulmonary arterial hypertension (PAH) in adults.

Pulmonary arterial hypertension is a serious condition characterized by high blood pressure in the arteries of the lungs. Sildenafil citrate helps in PAH by relaxing the blood vessels in the lungs, which allows blood to flow more easily. This reduces the workload on the heart and improves symptoms such as shortness of breath and exercise capacity.

The role of Sildigra 100 mg in treating PAH is primarily based on its vasodilatory effects. By inhibiting the enzyme phosphodiesterase type 5 (PDE5), sildenafil citrate increases the levels of cyclic guanosine monophosphate (cGMP), a chemical that promotes relaxation of smooth muscle cells and dilation of blood vessels. This vasodilation leads to a reduction in pulmonary arterial pressure and an improvement in pulmonary circulation.

When used for PAH, the dosage of sildenafil citrate is typically higher than that used for erectile dysfunction. However, it's essential to use Sildigra or any medication containing sildenafil citrate for PAH only as prescribed by a healthcare provider. They can determine the appropriate dosage and monitor its effectiveness and any potential side effects.

It's important to note that Sildigra 100 mg is not approved specifically for the treatment of PAH. Instead, there are other sildenafil citrate formulations, such as Revatio, which are specifically approved for the treatment of PAH. If you have PAH or any concerns about your treatment, it's crucial to consult with your healthcare provider for personalized advice and guidance.