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Priapism, a prolonged and often painful erection lasting more than four hours, is a rare but potential side effect of medications like Tadarise Pro 20 mg, which contains tadalafil as its active ingredient. While priapism is more commonly associated with other PDE5 inhibitors like sildenafil (Viagra), it can still occur with tadalafil, albeit rarely.

Here's why priapism can occur with medications like Tadarise Pro 20 mg:

Blood flow regulation: Tadarise Pro 20 Mg , like other PDE5 inhibitors, works by increasing blood flow to the penis during sexual stimulation. In some cases, this increased blood flow may persist longer than desired, leading to prolonged erections.

PDE5 enzyme inhibition: PDE5 inhibitors block the activity of the enzyme phosphodiesterase type 5, which regulates the breakdown of cyclic guanosine monophosphate (cGMP) in the penis. When this enzyme is inhibited, cGMP levels remain elevated, promoting prolonged smooth muscle relaxation and increased blood flow to the penis.

While priapism is a potential side effect of Tadarise Pro 20 mg, it's essential to note that it is relatively rare. However, if you experience an erection lasting longer than four hours while taking Tadarise Pro 20 mg, it's crucial to seek immediate medical attention. Priapism, if left untreated, can lead to tissue damage and permanent erectile dysfunction. Your healthcare provider can provide appropriate treatment to resolve the priapism and prevent complications.