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Fildena 100 mg contains sildenafil citrate as its active ingredient, which belongs to a class of medications known as phosphodiesterase type 5 (PDE5) inhibitors. Sildenafil works by selectively inhibiting the enzyme phosphodiesterase type 5, which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis.

Here's how Fildena 100 mg affects blood circulation:

Relaxation of Blood Vessels: When a man is sexually stimulated, nitric oxide (NO) is released in the erectile tissue of the penis. Nitric oxide stimulates the enzyme guanylate cyclase, resulting in increased levels of cyclic guanosine monophosphate (cGMP). This leads to relaxation of the smooth muscles in the blood vessels of the penis, allowing them to dilate and increase blood flow.

Increased Blood Flow to the Penis: By inhibiting the enzyme phosphodiesterase type 5 (PDE5), sildenafil citrate helps to prevent the breakdown of cGMP. This allows cGMP levels to remain elevated, promoting continued relaxation of the smooth muscles and vasodilation of the blood vessels in the penis. As a result, there is an increased inflow of blood into the erectile tissue, leading to an erection.

Enhanced Erectile Response: The increased blood flow to the penis facilitates the achievement and maintenance of an erection during sexual stimulation. However, it's important to note that sildenafil citrate does not directly cause an erection; sexual stimulation is still required to initiate the physiological processes that lead to erection.

Systemic Effects: While the primary action of sildenafil citrate is on the blood vessels of the penis, it can also cause vasodilation in other parts of the body. This can lead to a temporary decrease in blood pressure. Therefore, individuals with certain cardiovascular conditions or those taking medications that affect blood pressure should use Fildena 100 mg with caution and under the guidance of a healthcare professional.

In summary, Fildena 100 mg works by enhancing blood circulation to the penis through the inhibition of phosphodiesterase type 5 (PDE5) enzyme, leading to vasodilation of penile blood vessels and improved erectile response during sexual stimulation.