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Silditop 100 mg contains the active ingredient sildenafil, which belongs to a class of medications known as phosphodiesterase type 5 (PDE5) inhibitors. The mechanism of action of Silditop 100 mg involves several steps:

Inhibition of PDE5 enzyme: After ingestion, sildenafil is absorbed into the bloodstream and reaches the smooth muscle cells of the penis. Once there, it selectively inhibits the enzyme phosphodiesterase type 5 (PDE5).

Elevation of cyclic guanosine monophosphate (cGMP) levels: Normally, during sexual arousal, the release of nitric oxide (NO) in the penis leads to the production of cyclic guanosine monophosphate (cGMP). cGMP is responsible for relaxing the smooth muscles in the penile arteries and corpus cavernosum, leading to increased blood flow into the penis and erection.

Enhanced vasodilation and blood flow: By inhibiting PDE5, Silditop 100 Mg prevents the breakdown of cGMP, allowing cGMP levels to remain elevated for longer periods. This leads to prolonged relaxation of the smooth muscles and enhanced vasodilation (widening of blood vessels) in the penis, resulting in increased blood flow and improved erectile function.

Promotion of penile erection: The increased blood flow into the penis results in a firm and sustainable erection, provided there is adequate sexual stimulation.

It's important to note that Silditop 100 mg, like other PDE5 inhibitors, does not directly cause an erection. Sexual arousal and stimulation are necessary for the medication to be effective. Silditop 100 mg simply enhances the body's natural response to sexual stimulation by facilitating the physiological processes involved in penile erection.

Overall, the mechanism of action of Silditop 100 mg helps to improve erectile function and treat erectile dysfunction (ED) by increasing blood flow to the penis and promoting the ability to achieve and maintain an erection sufficient for satisfactory sexual activity.